50/50 Trailer Starring Seth Rogen and Joseph Gordon-Levitt

For a few years now we’ve been hearing about an upcoming project from Seth Rogen that would attempt to do the impossible: make a comedy about cancer. His friend Will Reiser wrote a script about his own experiences as a cancer survivor called I’m With Cancer that made the Black List for Best Unproduced Screenplays back in 2008, but no studios wanted to touch it with a ten foot pole. Eventually, with Rogen attached to star in and produce the film along with his partner Evan Goldberg, Summit Entertainment finally came on board, as did director Jonathan Levine (The Wackness). The movie was also renamed to 50/50, and now the first trailer has arrived online.

Joseph Gordon-Levitt plays Adam, a 27-year-old man who is diagnosed with rare form of spinal cancer and is given a 50% chance to survive. Together with his best friend (Seth Rogen), his mother (Anjelica Huston), his girlfriend (Bryce Dallas Howard), and his therapist (Anna Kendrick), they must learn to cope with the situation and, hopefully, live through it. There’s no getting around the fact that this story will require a delicate touch, and the fact that it is an R-rated comedy will only make the task that much more difficult. But it’s also refreshing to see a topic like this being dealt with using edgy humour instead of as a straightforward drama. If they can pull it off, I think it goes without saying that this could be one of the best movies of the year. 50/50 hits theatres on September 30th; check out the trailer after the jump and see what you think.

  • Gil

    didn’t jason bateman have cancer in a movie?

  • http://www.imdb.com/title/tt0103877/

    Never heard of it myself, but it sounds like Fanboys kinda ripped it off.

  • Dave

    Looks good.

  • Very solid trailer. But doesn’t the guy in the middle during the trailer prologue serve as a spoiler?

    Have been down on Rogen of late – overexposure, for one thing. But this material suits him beautifully.

  • Niklas

    It looks like it could be a really good movie but after having a sister who passed away from cancer I just don’t see anything funny about it. It might work as a movie but not as a comedy.

  • 1138sw


    I definitely empathize Niklas. I lost my dad to cancer and I don’t see how Cancer as one of the main topics can be funny but then I don’t think this movie is meant for you or me.

    But I will say I liked the trailer and it doesn’t look like a straight comedy but more like a comedy/drama. Like Gordon Levitt a lot but don’t know if I could sit through this.

  • T. Heilman

    Didn’t Funny People tackle this subject as a side-plot?

  • i really don’t think anyone in the movie is going to be making Cancer jokes, i’m pretty sure the so called “comedy” is just going to be a tonal thing, in that the treatment of the subject matter is gonna be lighter as opposed to something like Magnolia’s treatment of cancer. And yeah Funny People kinda did but I dont think Sandler actually had cancer in it i think it was like leukimeia or something.

  • bakaneko718

    this looks like it might be good.

  • Jo pour


    Leukemia is a type of cancer.

  • Napalm

    *Funny People flashback*

    Btw, I don’t think they’re exactly gonna make jokes about cancer itself, rather use it as a plot device. Trailer looks okay to me… started off good but went down the typical indie film route a little towards the end.

  • :P i feel stupid…

  • Jose

    Saw a sneak preview of this film a couple months back and it’s one of the best movies I have ever seen with superb action from Levitt. Cancer isn’t so funny but their conversations and stuff that happens around them is pretty hilarious. Can’t wait to see it in theaters.

  • Nicole

    I’m 37 years old and currently going through chemotherapy for ovarian cancer. I was psyched when I saw this preview because, as a young person with cancer, we are just about invisible. When I go to get my chemo I’m surrounded by older people who feel sorry for me. If there’s anything I need, it’s more humor in my life. No, cancer isn’t funny but a story of a young person and a devoted friend helping them through it is definitely something I can’t wait to see. Plus, I love Jospeh-Gordon Levitt! There are a lot of us today living with cancer as a chronic disease and we need to be inspired too.

  • I’m 30, and have terminal bowel cancer. This movie looks hilarious. Its a dark subject, but one that needs lightening up, and no doubt a story that needs to be told.