From his inauspicious start on such TV shows as The Facts of Life, Roseanne and E.R. to his current status as eminent Hollywood A-lister, George Clooney has had a pretty interesting career. He has appeared in everything from massive blockbusters to unfortunate flops, awards contenders to trashy genre films, serious political dramas to goofy comedies. He has also written, directed and produced plenty of his own material and won a couple of Oscars as well. It’s difficult to boil his career down to just one cinematic achievement… but that’s exactly what we’re asking you to do! So what is the George Clooney’s best movie to date? Cast your vote in our latest poll and then sound off in the comments below.